tiket kereta toko bagus berita bola terkini anton nb Aneka Kreasi Resep Masakan Indonesia resep masakan menghilangkan jerawat villa di puncak recepten berita selebritis terkini game online hp dijual windows gadget jual console voucher online

Geographic tongue treated with topical tacrolimus

Masaya Ishibashi, Genichi Tojo, Masahiko Watanabe, Takahiro Tamabuchi, Takashi Masu, Setsuya Aiba


Background: Geographic tongue, or benign migratory glossitis, is usually an asymptomatic inflammatory disorder of the tongue mucosa of unknown etiology. It is characterized by circinate, erythematous, ulcer-like lesions of the dorsum and lateral border of the tongue due to loss of filiform papillae of the tongue epithelium. Symptomatic treatments have not been evaluated rigorously.

Main observation: We describe herein two cases of adult patients with persistent and painful geographic tongue successfully treated with topical application of 0.1% tacrolimus ointment.

Conclusion: To our knowledge, this is the first report of successful treatment with topical 0.1% tacrolimus for symptomatic geographic tongue. Clinical trials are needed to confirm the efficacy and the safety of topical tacrolimus in treating geographic tongue.


Ishibashi M, Tojo G, Watanabe M, Tamabuchi T, Masu T, Aiba S. Geographic tongue treated with topical tacrolimus. J Dermatol Case Rep. 2010; 4(4): 57-59.


benign migratory glossitis; calcineurin inhibitors; geographic tongue; tacrolimus; treatment

Full Text: Full Text HTML Full Text PDF

2007-2018 © Specjalisci Dermatolodzy

The JDCR content may not be distributed, used, adapted, reproduced, translated or copied for any commercial purpose in any form without prior permission of the publisher. Any use of this Journal in whole or in part, must include the customary bibliographic citation and its URL.